by The Global Allan-Herndon-Dudley Syndrome Treatment Market involves products that help treat the symptoms of Allan-Herndon-Dudley syndrome (AHDS). AHDS is a rare genetic disorder caused by mutations in the thyroid hormone activating gene THAP11 that prevents the proper activation of thyroid hormones. Individuals with AHDS experience intellectual disability, weak muscle tone and delayed development. Treatment options for AHDS include thyroid hormone replacement therapy using synthetic thyroid hormones such as levothyroxine. Gene therapy is also being explored as a promising treatment approach that uses modified viruses to deliver functioning copies of the defective THAP11 gene to thyroid cells.
The Global Allan-Herndon-Dudley Syndrome Treatment Market is estimated to be valued at US$ 13.36 Mn in 2024 and is expected to exhibit a CAGR of 5.5% over the forecast period 2024 to 2031.
Advancement in gene therapy is providing hope for effective management of the disorder. With no approved cure currently available, the market offers scope for companies developing innovative treatment options.
Key Takeaways
Key players operating in the Global Allan-Herndon-Dudley Syndrome Treatment Market are Rare Thyroid Therapeutics International AB and Erasmus Medical Center. Rare Thyroid Therapeutics is conducting clinical trials for its lead gene therapy candidate RTT101 for the treatment of AHDS.
Growing awareness about rare genetic conditions and associated treatment options is fueling the Global Allan-Herndon-Dudley Syndrome Treatment Size for Allan-Herndon-Dudley Syndrome treatment products. Government support for orphan drug development is also encouraging pharmaceutical investments.
Pharmaceutical companies are expanding their geographical presence through collaborations to address the needs of underserved markets. Rare Thyroid Therapeutics has partnered with American THYRONYX for developing and commercializing RTT101 in North America.
Market Key Trends
Advancement in gene therapy technology is a major trend in the Global Allan-Herndon-Dudley Syndrome Treatment Market. Gene therapy involves delivering functioning gene copies to replace defective genes causing rare genetic disorders. Global Allan-Herndon-Dudley Syndrome Treatment Companies are developing novel gene therapy candidates like AAV-based vector products that can efficiently deliver the normal THAP11 gene inside thyroid cells. If successful, gene therapy may emerge as a cure for AHDS in the coming years.
Porter’s Analysis
Threat of new entrants: The regulations regarding clinical trials and drug approval process make it difficult for new companies to enter the market.
Bargaining power of buyers: The buyers have limited bargaining power given the complexity of the disease and lack of treatment options currently available.
Bargaining power of suppliers: Due to the rare nature of the disease and limited research focus area, suppliers hold advantage over pricing.
Threat of new substitutes: No strong substitutes currently exist for the disease.
Competitive rivalry: Limited companies are involved in research and development leading to high competition.
Geographical Regions
North America currently accounts for the largest share of the global market primarily owing to greater adoption of treatment drugs and increasing research funding in the region.
Asia Pacific excluding Japa is expected to witness highest growth over the forecast period supported by growing healthcare expenditure, large patient population and improving access to diagnosis and treatment in emerging Asian countries.
*Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it
Vaagisha Singh
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