New research published in the Journal of Hepatology indicates that increased tryptophan intake may contribute to the growth of liver cancer cells. Tryptophan, an essential amino acid, is necessary for the production of proteins in the human body. However, recent findings suggest that it may also play a role in the development and progression of liver cancer.
The study, conducted by researchers at the University of California, San Diego, involved analyzing the dietary habits and health records of over 1,000 liver cancer patients and 1,000 healthy individuals. The results showed that those with liver cancer consumed significantly more tryptophan than the control group.
Further investigation revealed that tryptophan metabolites, specifically kynurenine and anthranilic acid, were elevated in liver oncology patients. These metabolites are produced when tryptophan is broken down in the body and have been linked to inflammation and oxidative stress, both of which are known to contribute to liver cancer.
The researchers also found that high tryptophan intake was associated with a more aggressive form of liver cancer and poorer prognosis. The study’s lead author, Dr. Xiaoyang Wang, stated, “Our findings suggest that tryptophan metabolism may be a promising target for the prevention and treatment of liver cancer.”
The study adds to the growing body of evidence linking diet and liver cancer risk. Previous research has shown that diets high in processed meats, sugary drinks, and saturated fats increase the risk of liver cancer. Conversely, diets rich in fruits, vegetables, and whole grains have been shown to protect against liver cancer.
The researchers emphasized the importance of further investigating the role of tryptophan in liver cancer and exploring potential interventions to reduce tryptophan intake or modulate its metabolism as a means of preventing or treating liver cancer.
a new study published in the Journal of Hepatology suggests that increased tryptophan intake may contribute to the growth of liver cancer cells. The findings indicate that tryptophan metabolites, such as kynurenine and anthranilic acid, may play a role in liver cancer development and progression. Further research is needed to explore potential interventions to reduce tryptophan intake or modulate its metabolism as a means of preventing or treating liver cancer.
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1. Source: Coherent Market Insights, Public Source, Desk Research
2. We have leveraged AI tools to mine information and compile it
Alice Mutum
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