July 19, 2024
DNA Synthesizer Market

Automation driving growth in the global DNA Synthesizer Market

The global DNA Synthesizer Market is estimated to be valued at US$ 4.30 Bn in 2023 and is expected to exhibit a CAGR of 20.% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

The global DNA Synthesizer Market is primarily driven by growing automation and adoption of high throughput DNA sequencing technologies in genomics research and healthcare applications. DNA synthesizers are instruments used by researchers for rapid, cost efficient and high quality production of DNA for various applications such as assembly of genes and genomes, gene expression studies, targeted genome engineering and cell-free protein synthesis. DNA synthesizers enable automation of labor-intensive and time-consuming manual DNA synthesis process.

Market Overview:
DNA synthesizers are used for producing both oligonucleotides having short sequences (20-100 base pairs) as well as larger gene fragments and plasmids. Based on techniques, the market is segmented into phosphoramidite and Hosphate chemical synthesis. Phosphoramidite chemistry accounts for major share as it allows high throughput and large-scale production of DNA. Key end users of DNA synthesizers include academic research institutes, pharmaceutical & biotechnology companies, diagnostic labs and contract research organizations. Increasing R&D investments and adoption of next generation DNA sequencing in precision medicine and drug discovery is expected to propel the demand for DNA synthesizers over the forecast period.

Market key trends:
The global DNA synthesizer market is witnessing several technological advancements focused on improving throughput, lengthening synthesizable DNA fragments, reducing cost per base synthesized and enabling benchtop gene synthesis. Major trends in the market include development of solid-phase oligonucleotide synthesizers with higher productivity, integration of CRISPR gene editing technologies with DNA synthesis for rapid genomic engineering applications and launch of hybrid DNA synthesizers combining microchip array synthesis with classical phosphoramidite chemistry. Adoption of continuous flow manufacturing platforms for DNA synthesis is also emerging to address the limitations of batch production. Such innovations are expected to make gene synthesis faster and more affordable, driving wider applications of DNA synthesizers across sectors.
Porter’s Analysis

Threat of new entrants: The threat of new entrants is moderate as the cost of setting up a DNA synthesizer manufacturing facilities is high requiring substantial R&D investments. However, the growing market size is attracting new players.

Bargaining power of buyers: The bargaining power of buyers is low to moderate as the market has several established manufacturers offering DNA synthesizers with varied product specifications. However, large buyers can negotiate on price.

Bargaining power of suppliers: The bargaining power of suppliers is moderate as raw materials required are specialty chemicals needing specialized manufacturing capabilities. However, established players have long-term supply agreements in place.

Threat of new substitutes: The threat of substitutes is low as DNA synthesizers have limited substitutes. Emerging technologies could pose some threat going forward.

Competitive rivalry: The competitive rivalry is high among established manufacturers owing to their large product portfolios and geographical presence resulting in pricing pressures.

Key Takeaways

The global DNA Synthesizer Market Growth is expected to witness high growth, exhibiting a CAGR of 20% over the forecast period, due to increasing demand for synthetic genes for research activities.

Regional analysis: North America dominated the market in 2022 accounting for more than 35% share owing to presence of majority of key players and research institutions in the region. Asia Pacific is expected to be the fastest-growing market over the forecast period backed by increasing R&D investments and development of pharmaceutical manufacturing facilities in China and India.

Key players: Key players operating in the DNA Synthesizer market are Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Danaher Corporation (Integrated DNA Technologies), GenScript Biotech Corporation, Eurofins Genomics, LGC Limited, BioAutomation Corporation, Bio-Rad Laboratories, Twist Bioscience Corporation, Hamilton Company, Expedeon AG, New England Biolabs, Nippon Genetics, LGC Biosearch Technologies. Thermo Fisher Scientific and Merck KGaA hold a significant share in the global market.

1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it