May 23, 2024

Anti-Inflammatory Drugs: Managing Pain Naturally

Anti-inflammatory drugs help manage and reduce inflammation, providing relief from pain, swelling and stiffness associated with various conditions. Let’s explore some of the main anti-inflammatory drug options available.

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

NSAIDs are among the most commonly used over-the-counter and prescription medications for inflammation. Ibuprofen (Advil), naproxen (Aleve) and celecoxib (Celebrex) are some examples of NSAIDs. They work by blocking cyclooxygenase (COX) enzymes that produce prostaglandins, chemicals in the body that cause inflammation and pain. As a result, NSAIDs can help relieve symptoms associated with arthritis, muscle strains, menstrual cramps and more.

While effective, NSAIDs do carry some risk of side effects with long-term or high dose use including stomach irritation, ulcers, kidney problems and increased risk of heart attack or stroke. They should usually only be taken as directed on the label for short-term relief of mild to moderate pain or inflammation. People with conditions like ulcers, kidney disease or heart conditions may need an alternate option or additional stomach protection.


Corticosteroids are a class of steroid hormones that have potent Anti-Inflammatory Drugs . Prescription corticosteroids like prednisone are sometimes used for short periods to treat severe arthritis, autoimmune conditions and allergic reactions. They work by reducing chemicals that cause inflammation systemically throughout the body.

While very effective for reducing inflammation, corticosteroids have more serious potential side effects compared to NSAIDs with long-term use such as increased risk of infections, high blood pressure, weight gain, osteoporosis and mental health issues. As a result, they are usually only taken for brief periods to get flare-ups under control before switching to a less risky alternative.

Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

For people with chronic inflammatory conditions like rheumatoid arthritis, disease-modifying anti-rheumatic drugs (DMARDs) may provide a good long-term treatment option. Rather than just treating symptoms, DMARDs work to slow down or prevent further joint damage by modifying the disease process itself. Common DMARDs include methotrexate, hydroxychloroquine, leflunomide and sulfasalazine.

While they take several months to become fully effective, DMARDs may allow some patients to reduce their use of other pain medications over time. Close medical supervision is required due to possible side effects such as liver toxicity, stomach upset and low blood cell counts with methotrexate. However, with monitoring, DMARDs provide a well-tolerated treatment alternative for long-term management of certain chronic inflammatory conditions.

Herbal Anti-Inflammatories

For centuries, herbal medicines have also been used worldwide to treat inflammation and related symptoms. Some promising natural anti-inflammatory options supported by research include turmeric, ginger, boswellia, devil’s claw and cannabidiol (CBD) from hemp plants.

Turmeric contains the active compound curcumin, which has powerful antioxidant and anti-inflammatory properties. Studies show turmeric may help relieve arthritis symptoms when taken regularly. Ginger contains compounds called gingerols that block inflammatory prostaglandins. It is often used as a natural alternative to prescription NSAIDs for pain relief.

Boswellia serrata is an herb known as Indian frankincense. Clinical trials found boswellia extracts as effective as NSAIDs in treating osteoarthritis without significant side effects. Devil’s claw is another herb traditionally used for joint inflammation in Europe. Research indicates devil’s claw contains compounds that inhibit pain-causing COX enzymes like NSAIDs.

CBD is a non-psychoactive compound found in hemp and cannabis plants. Preclinical research suggests CBD acts on multiple targets in the body’s endocannabinoid system to reduce inflammation. Studies on animals and humans have found CBD-based treatments effective at relieving arthritis pain when applied locally to the skin or taken orally. More research is still needed on appropriate dosing and long-term safety. While side effect risk is generally lower than prescription medications, it’s important to seek guidance from a knowledgeable herbalist or healthcare provider before using herbal remedies.

In summary, numerous anti-inflammatory treatment options exist for managing pain, discomfort and functional impairment from conditions involving inflammation. NSAIDs, corticosteroids, DMARDs and natural anti-inflammatories all have roles to play depending on a person’s specific condition and health needs. Working closely with your doctor to find the safest and most suitable anti-inflammatory treatment regimen will provide the most effective relief over the long run.

1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it