Southern blotting is a laboratory technique that is used to detect the presence of a specific DNA sequence in DNA samples that have been restricted, separated by gel electrophoresis, and transferred to a membrane. It is used for detection of DNA fragments with complementary nucleotide sequences. The technique involves blotting a gel containing restriction enzyme-digested DNA fragments onto a nylon or nitrocellulose membrane. A radioactive or non-radioactive probe is used to label DNA fragments identical or similar to the target gene/DNA fragment and allow their detection on the membrane. Southern blotting has applications in areas such as genetic fingerprinting, identification of diseases, forensics, and gene expression analysis.
The global Southern blotting market is estimated to be valued at US$ 3.23 billion in 2024 and is expected to exhibit a CAGR of 6.8% over the forecast period 2024 to 2031, as highlighted in a new report published by Coherent Market Insights.
The global market has been witnessing significant growth owing to rising demand from biotechnology and pharmaceutical industries which engage in genetic research for developing therapeutic drugs and novel treatments. Southern blotting technique finds widespread use in genetically modified crops assessment, validation of transgenic organisms, and food safety testing performed by these industries.
The growth of the global southern blotting market is expected to be driven by increasing demand from the biotechnology and pharmaceutical industries over the forecast period. These industries extensively utilize southern blotting techniques for research activities involving identification of genetic patterns, gene expressions studies, and drug development processes which requires validation of specific DNA sequences. Additionally, the increasing applications of southern blotting in forensic sciences for DNA fingerprinting and parental testing is also expected to support the market growth during the forecast period. The advent of new rapid techniques such as PCR and DNA microarrays have posed a restraint on the southern blotting market as these newer methods are considered more efficient and robust. However, southern blotting still retains advantages over alternate techniques in scenarios demanding high specificity and where RNA/DNA quantification is important. Continuous innovations towards automation and streamlining of southern blotting workflows are expected to offer lucrative opportunities for market players over the coming years.
The southern blotting market is dominated by the DNA and RNA detection segment. This segment holds more than 60% share of the overall southern blotting market as southern blotting is the gold standard technique for DNA and RNA detection. It is widely used for detecting DNA or RNA fragments separated by agarose gel electrophoresis in biomedical research for diagnostic purposes.
Political: Regulations related to clinical trials and patent laws impact the research and development in this market. Supportive government funding programs promote the growth.
Economic: Increasing research expenditure in life science and biotechnology drives the demand. However, high cost of instruments poses challenges.
Social: Rising prevalence of genetic disorders and infectious diseases increases the clinical testing requirement. Growing biomedical sector influences positively.
Technological: Advancements in blotting techniques like capillary transfer and automated systems improve efficiency. Development of sensitive probes and non-radioactive labeling methods boosts the application scope.
The Global Southern Blotting Market Size is expected to witness high growth over the forecast period. The global Southern blotting market is estimated to be valued at US$ 3.23 billion in 2024 and is expected to exhibit a CAGR of 6.8% over the forecast period 2024 to 2031.
North America accounts for around 40% share of the global southern blotting market. This can be attributed to extensive R&D activities for drug discovery and preclinical research in the US. Growing stem cell research and clinical testing in Canada supports the regional growth.
Key players operating in the southern blotting market are Ganeden, Sabinsa Corporation, UAS Laboratories, Sanzyme, Mitsubishi Chemical Foods Corporation, Mystical Biotech Pvt. Ltd., Aumgene Biosciences, Unique Biotech Ltd., Nebraska Culture, and Syngem Biotech. Key players are focusing on new product launches and strategic collaborations to strengthen their market position.
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it